| CONTINUING NURSING EDUCATION SERIES NO: 37 |
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| Year : 2019 | Volume
: 20
| Issue : 2 | Page : 131-140 |
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Organophosphate poisoning: Overview, management and nursing care
Mary Jancy Joy, Bharathy Radhakrishnan, Meenakshi Sekar, Shirley David
Department of Medical Nursing, College of Nursing, CMC, Vellore, Tamil Nadu, India
Correspondence Address:
Mrs. Mary Jancy Joy
College of Nursing, CMC, Vellore, Tamil Nadu
India
 Source of Support: None, Conflict of Interest: None  | 1 |
DOI: 10.4103/IJCN.IJCN_24_20
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Acute poisoning by organophosphates (OPs) for suicidal purpose poses a major problem, leading to high mortality in the developing countries. This occurs as OPs irreversibly bind to acetylcholinesterase, leading to the accumulation of acetylcholine at the neuromuscular junction and subsequent over-activation of cholinergic receptors in various parts of the body. Early identification of the signs and symptoms and prompt management enhance better outcomes reducing mortality. Atropine, oximes, neuroprotection and quality care remain the mainstay of treatment for OP poisoning and can reverse the life-threatening features of acute poisoning. Supportive treatment includes maintaining airway, breathing, circulation and decontamination of the poison. Nurses working in the critical care units play a vital role in monitoring the patient closely, providing quality nursing care and thereby preventing complications.
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